Endocannabinoids

It's not just CBD!　What is the function of the endogenous cannabinoid system (ECS) supported by "water"?

1. Moisture is the basic environment for ECS function

The ECS (endocannabinoid system) is responsible for maintaining homeostasis in the body. It is involved in body temperature regulation, appetite, pain, inflammation, mood, sleep, immunity, etc.

When water is insufficient, metabolism, neurotransmission, and enzymatic reactions at the cellular level do not work well, and the ECS slows down.



2.Dehydration triggers a stress response

When you are dehydrated, cortisol (stress hormone) is secreted, and the ECS works to suppress it.

However, chronic water deprivation can also limit the ability of the ECS to regulate, which can worsen inflammation, mood disorders, and insomnia.


3. Water is also required for the synthesis of endocannabinoids

Endogenous cannabinoids (anandamide and 2-AG) are molecules derived from lipids, but enzymes are involved in their synthesis and degradation, and the water environment affects enzyme activity.

Since enzymatic reactions basically work optimally in a water-soluble environment, dehydration poses a risk of causing metabolic disorders.

4. Hydration and nervous system health

The ECS is also widely distributed in the central nervous system, and water balance also affects signaling in the brain.

Especially in the elderly, it is difficult to feel thirsty, so the regulatory mechanism involved in the ECS is likely to decline, which can cause symptoms such as constipation, insomnia, and depression.

5.Water as an environmental factor that supports the work of CBD and cannabinoids

Phytocannabinoids such as CBD support the ECS, but water is essential for absorption, transport, and action in the body.

Water-soluble CBD is especially essential for moisture to be effective. In the dehydrated state, it is not well dispersed and absorbed, making it difficult to exert its effectiveness.

Summary

Water is like the "soil" of the ECS. In a state of lack of fluids, the ECS cannot function well. In addition to diet and CBD intake to regulate the ECS, "drinking water frequently" is the basis for maintaining fundamental health.

Every summer"I can't eat because I'm tired in the summer" "I can't sleep without air conditioning"I often hear voices saying.
On the other hand, there are people who can live well in the same environment. Where does this difference come from?

The keyword is "heat acclimatization".
This time, we will talk about the mechanism by which the body gets used to heat, the relationship with the endocannabinoid system (ECS),
And we will explain how to use CBD to support you.



1. What is heat acclimatization?

Heat acclimatization is an adaptive response in which the human body changes to cope with rising temperatures.
Specifically, the following changes occur:
1.Increased sweating and easier to regulate body temperature
2.Reduced salt content in sweat and reduced mineral loss
3.Reduces the increase in heart rate and body temperature
4.Reduces the risk of heat stroke

This acclimatization occurs gradually over a few days ~ 2 weeks, and is triggered by moderately sweaty activities during the day. On the other hand, if you are only in air-conditioned rooms, heat acclimatization is less likely to occur.


2.Relationship between ECS and heat tolerance
The ECS (endogenous cannabinoid system) is a regulatory mechanism that maintains homeostasis in body temperature, stress, immunity, energy metabolism, etc.
If this ECS is working well, the following adjustments will go smoothly:
1.initiation and suppression of sweating
2.Balance adjustment of the autonomic nervous system (sympathetic and parasympathetic nerves)
3.Suppression of inflammatory response
4.Improve the quality of sleep and recovery

In a hot environment, the body is more susceptible to stress, but if the ECS is working well, it may be able to suppress overreactions and acclimatize smoothly.

3.The importance of diet, hydration, and exercise

#食事
1. In summer, the stomach tends to weaken. Choose not only cold foods, but warm and easy to digest.
2. Minerals such as magnesium, potassium, sodium, and zinc are easily lost with sweat, and miso soup, natto, vegetables, seaweed, and pickled plums are useful.

#moisture
1.Frequent replenishment before feeling thirsty is the iron rule. Mineral water, reduced water, barley tea, etc. are recommended.
2.Sweet soft drinks are counterproductive. It can cause blood sugar spikes, dehydration, and sluggishness.

#exercise
1.Walking and light muscle training to encourage light sweating during the day is a shortcut to heat acclimatization.
2.If you get too used to the air conditioning environment, your sweating function will decline. Be conscious of exercising during the cool hours of the morning and evening.

4.How can CBD be used?

CBD is very effective against insomnia, stress, and autonomic nervous system disturbances associated with heat.

Utilization points
1.Take before sleep at night: Reduces sympathetic overactivity and supports deep sleep
2.Used when you feel excessive tension or irritability during the day
3.Helps recover from fatigue after exercise: CBD can also help restore muscles and reduce inflammation

In particular, water-soluble CBD is absorbed quickly and has good absorption efficiency when sweating and circulation are increased. In summer, water metabolism in the body is also intense, so water-soluble types are suitable.




Summary: How to build a body that can withstand summer

1.Heat acclimatization is the same as training. Resistance becomes more resistant by getting used to it little by little
2.If the ECS is functioning properly, it will be easier to acclimatize and the body will be less likely to get tired.
3.Balance of diet, water, and exercise is the basic
4.CBD is also an effective support for preventing summer fatigue as a regulator of the ECS

When disparate disorders are connected by a single line

― Fibromyalgia, migraine, IBS and the perspective of "cannabinoid deficiency" ―


This blog is based on what we talked about in the Amazing Power of the Endocannabinoid System Series Episode 6 Deep Dive "Self-Care and ECS".
This is a supplementary article that delves further with my own changes and observations in my body.
Whether you have watched the video or not, please read it as a hint to face your body

? Watch the video: "The moment when fibromyalgia, migraine, and IBS connect as one"

Hello.
If you have reached this page, you may be:
**You may be suffering from fibromyalgia, migraines, irritable bowel syndrome (IBS)**, or more.

Even when I went to the hospital, I was told that there was nothing abnormal or that it might be due to stress.
But there are certainly symptoms.
Pain, nausea, abdominal pain, anxiety, fatigue, inability to sleep...
The disparate discomfort may actually lead to a common cause.

The moment I realized this,
My experience as a doctor and my own experience finally became a "single line".
On this page, we will tell you about this new perspective, "cannabinoid deficiency," and the "endogenous cannabinoid system (ECS)" that supports it in an easy-to-understand manner.

What is cannabinoid deficiency?

Clinical Endocannabinoid Deficiency (CECD) = Cannabinoid Deficiency
This concept was coined by the American neurologist Dr.. It was proposed by Ethan Russo.

According to his theory, when the function of the "endocannabinoid system (ECS)" in our body decreases,
It is believed that various disorders such as pain, inflammation, indigestion, anxiety, insomnia, and immune disorders can occur.

In particular, the following three diseases are thought to be closely related to ECS dysfunction.
*Fibromyalgia
*migraine
*Irritable bowel syndrome (IBS)

In other words, these things, which were thought to be "separate diseases", are actually the same roots. That's the way of thinking.

What is the Endocannabinoid System (ECS)?


The ECS is the "balance system" that our body is inherently inherent.
It works all over the body to maintain homeostasis.
* Cranial nervous system: emotions, memory, pain perception
* Immune system: control of inflammatory response
*Gastrointestinal tract: intestinal movement and inflammatory reactions in the intestines
*Autonomic nervous system: Balance of sympathetic and parasympathetic nervous systems

If this ECS is working properly, even if there is some stress, pain and anxiety will be supported by the "ability to recover on its own".
However, if the ECS does not work well due to chronic stress or disturbances in the living environment,
Your body begins to show signs of discomfort.


Reasons for overlapping symptoms ~It may be a disturbance in the ECS~

■ Fibromyalgia
The main symptoms include chronic pain throughout the body, fatigue, and sleep disturbances.
In addition to nerve hypersensitivity, called central sensitization, it is thought that a decrease in the function of the ECS (endocannabinoid system) is involved.



■ Migraine
In addition to throbbing headaches, it is characterized by nausea and sensitivity to light and sound.
Here, the interaction between the serotonin system and the ECS is important, and disturbances in the coordination of the ECS may be involved in the development of migraine.



■ Irritable bowel syndrome (IBS)
Gastrointestinal symptoms such as abdominal pain and repeated diarrhea and constipation are observed.
In addition to abnormal ECS in the intestinal tract, the imbalance with intestinal bacteria is also thought to be behind this symptom.


All of them seem to be disjointed at first glance,
In fact, it has been found that "the brain, gut, immunity, and emotions are connected."
At the heart of this is a coordination system called ECS.

How does CBD support the ECS?

CBD (cannabidiol) is a natural cannabinoid found in plants,
It is a supporting ingredient that indirectly regulates the function of the ECS.
1.Inhibits the breakdown of endogenous cannabinoids (anandamide)
2.relieves inflammation and pain signals
3.Suppresses nervous excitement caused by anxiety and stress
4.Supports the balance of the autonomic nervous system

Some people feel that incorporating CBD has reduced their pain, allowed them to sleep, and stabilized their mood.
This may not be just a symptomatic treatment, but an opportunity to regain your original balance.

But sometimes CBD alone isn't enough

In fact, you may not see immediate improvement with CBD.
The reasons for this can vary, but the following may be at play.
*Severe ECS dysfunction and long recovery
*Inadequate CBD intake or quality (e.g., fat-soluble or water-soluble)*?Lack of sleep and excessive stress keep up with ECS recovery
* Other factors such as nutrition, gut health, and exercise habits remain unadjusted

That's why it's so important to take a look at your entire life while incorporating CBD.

5 self-care to regulate the ECS

1.Consume omega-3 fatty acids (blue fish, sesame oil, etc.)
2.Keep doing light exercise (walking, stretching, yoga, etc.)
3.Sleep well (review your sleep environment, refrain from using your smartphone before bed, etc.)
4.Letting go of stress (deep breathing, meditation, spending time in nature)
5.Improve the intestinal environment (be aware of fermented foods and dietary fiber)

Because ECS is a network that spreads throughout the body,
Small daily choices and habits have a big impact on your future physical condition.

◆ Postscript: As my own feeling

Actually, I myself have migraines.
And I have been suffering from strong tension and stiffness from my back to my shoulders for many years, as if the same mechanism as fibromyalgia is suspected.

Even if you think you have medical knowledge,
Before I took CBD, I myself may have been a classic example of an imbalance in my ECS.

And when I encountered CBD,
Little by little, I began to listen to my body's voice,
Right now, I'm in the process of reviewing not only CBD, but also my lifestyle itself.
* Moderate exercise
*Ideas for sleeping well
* Balanced diet
*How to let go of stress

All of them are "I knew but couldn't do it".
However, by incorporating them little by little, I feel that my body is definitely changing.

Poor health is not "my fault".
However, the ability to adjust is "within me".
I am now experiencing this firsthand.