Given that cannabis has been used for medical purposes for a long time, it's no surprise that cannabinoids like CBD and THC are gaining traction.
However, in the 20th century, as a result of the legalization of cannabis in many countries, research on its medicinal properties has stagnated for a long time.
Later, with scientific and technological advances, the properties of cannabinoids were rediscovered, and the possibilities in the medical field began to expand.
Charlotte's story and the turning point of CBD
A major reason why CBD extracted from cannabis has once again attracted attention in the medical field is the story of Charlotte Figgy, who has an intractable epilepsy called Dravet syndrome.
Charlotte had suffered from frequent and severe seizures since childhood, and conventional treatments were ineffective, leaving her family in despair.
However, when she used CBD oil on her, the frequency of her seizures decreased dramatically. A documentary program featuring this miraculous result attracted attention from all over the world.
Discovery of the endocannabinoid system
While studying how CBD and THC work in the body, we discovered the endocannabinoid system (endocannabinoid system). This system plays a crucial role in regulating physiological processes such as pain, inflammation, immune function, and nerve transmission, which are naturally produced by our bodies.
While research is still ongoing, it has been revealed that imbalances in this system are associated with a variety of diseases, including epilepsy and neurological disorders. In the treatment of epilepsy, in particular, the potential of new therapies targeting this system is attracting attention.
Difference Between CBD and THC
One of the reasons CBD is particularly noteworthy is its lack of psychoactive effects.Because THC has psychoactive effects (the so-called "high" sensation), regulated in many countries. On the other hand,Because CBD has no psychoactive effects, high safety, and advanced application in the medical field. Interestingly, CBD and THC have very similar chemical structures and some overlapping effects. This has accelerated research into a combination of the two treatments and the use of CBD alone.
The Birth of Kriya Hops and the Evolution of CBD Research
Familiar with Ayurvedic knowledge from a young age, Dr. Joseph overcame the challenge of THC's psychoactive effects and embarked on the challenge of searching for botanicals containing CBD. He then focused on hops, a type of hemp plant, and discovered a unique variety that contains CBD in hops but does not produce THC at the genetic level. immobilize this variety,「Kriya」I named it and obtained a plant patent in the United States.
CBD Quality Control and Biological Activity Assessment
Dr. Joseph then developed technology to accurately assess the quality and effects of CBD. Reacts specifically to natural CBDMonoclonal AntibodiesIt is now easier to detect CBD that has been denatured during the extraction process and processing. By using this antibody, it was possible to quantify the extent to which CBD binds to CB2 receptors in the body, or binding affinity (biological activity).
Based on this technology, Dr. Joseph established an evaluation system that expresses the biological activity of CBD as 0~1, and also obtained a patent for this technology. This evaluation method has provided a groundbreaking method that allows for scientific verification of the quality and effectiveness of CBD products.
Biological activity that varies greatly depending on the plant site
As a result of research using this technology, among hops (Kriya) and hemp-derived CBD,CBD extracted from inflorescences has the highest biological activityIt has been revealed that it has This indicates that CBD derived from inflorescences binds most strongly to CB2 receptors and exerts its full effect.
Based on this, Kriya Hops is developing products centered on inflorescences.Compared to conventional hemp-derived CBD, Kriya has higher biological activity and is expected to be applied to various diseases, including epilepsy.
Challenges of Hemp and Synthetic CBD with Low Bioactivity
Further research by Dr. Joseph found that hemp-derived CBD products, synthetic CBD, and even CBD sold as drugs have very low biological activity.In particular, it is unknown whether any of the hemp products currently on the market are made using "inflorescences only".Against this background, we can see that the manufacturing process and raw materials of CBD products have a significant impact on biological activity.
Synthetic CBD, even if chemically pure, often does not have the same effects as naturally derived CBD. As a result, the importance of the complex effects of naturally derived CBD is reaffirmed.
Maximize the healing power of plants
Dr. Joseph views Kriya not as a Western medicine medicine, but from the perspective of "bringing out the healing power of plants." This idea aligns with Ayurvedic and naturopathic concepts, suggesting an approach that respects the human self-healing power.
As a fellow doctor, I deeply sympathize with this idea and am also working to spread Kriya in Japan. Kriya is not just about controlling symptoms, but also about providing a new form of health care that balances the patient's entire body. This activity isIt plays a crucial role in spreading the potential of natural remedies not only to patients themselves, but also to their families and healthcare professionals.
Kriya brings hope to people with epilepsy
While many patients with epilepsy can control their seizures with appropriate treatment, many patients are anxious during treatment, reduction, or even after stopping medication. Kriya can be of great help to these patients.
There are increasing reports that using Kriya can reduce anxiety during seizure signs and stressful situations, and prevent seizures themselves. One patient said that using Kriya made her feel "Kriya in her head" and improved her quality of life even after the drug reduction began. A major feature of Kriya is that it does not have the side effects such as drowsiness, which are common with conventional drugs, and can improve symptoms in a natural way.
And as an approach to non-convulsive seizures, which are common in undiagnosed epilepsy patients and older adults, Kriya shows new potential. As a natural remedy for these patients to live their lives with peace of mind, Kriya has a lot of promise.